OCR A-Level Biology A (H420)
A-Level Biology
Answer sheet
Module 4 Biodiversity, evolution and disease
Separate mark scheme — do not issue with the student worksheet
Time guide: — · Questions: 32 · Total marks: 104
Written in OCR Biology A style. Use the data booklet ideas where relevant. Show statistical working.
Indicative marking points. Award marks for equivalent scientific or mathematical wording. Do not issue this sheet with the student worksheet.
1. State what is meant by the genetic code.
[1 mark]
- triplet, degenerate, non-overlapping, universal
2. State what is meant by transcription.
[1 mark]
- DNA → mRNA in the nucleus
3. State what is meant by translation.
[1 mark]
- mRNA + tRNA + ribosome → polypeptide
4. State what is meant by a mutation.
[1 mark]
- change in DNA base sequence
5. State what is meant by meiosis.
[1 mark]
- two divisions, haploid gametes, variation
6. State what is meant by natural selection.
[1 mark]
- differential survival and reproduction
7. State what is meant by speciation.
[1 mark]
- new species form when gene flow stops
8. State what is meant by taxonomy.
[1 mark]
- classification into domain to species
9. State what is meant by biodiversity.
[1 mark]
- variety of species, genetic and habitat
10. State what is meant by an antibody in immunity.
[1 mark]
- specific protein from plasma cells
11. Grace is asked about the genetic code in a OCR Biology paper.
(a) [2 marks]
- codons code for amino acids
12. Grace is asked about transcription in a OCR Biology paper.
13. Grace is asked about translation in a OCR Biology paper.
14. Grace is asked about a mutation in a OCR Biology paper.
(a) [2 marks]
- substitution, insertion, deletion
(b) [3 marks]
- frameshift is usually worse
15. Grace is asked about meiosis in a OCR Biology paper.
(a) [2 marks]
- crossing over and independent assortment
(b) [3 marks]
- fertilisation adds more variation
16. Grace is asked about natural selection in a OCR Biology paper.
(a) [2 marks]
- allele frequencies change
(b) [3 marks]
- directional or stabilising
17. A DNA sequence has 600 bases. Maximum amino acids
18. Chi-squared: 3:1 expected of 80 plants. Expected recessive
19. Index of diversity N(N−1)/Σn(n−1). If N=10 and Σ=12, D
20. Heterozygous cross Aa × Aa. Probability of aa
21. A gene pool has p=0.8. If HWE, frequency of heterozygotes
22. A 4-base sequence has 4⁴ possible combinations
23. Grace carries out a OCR-style required practical linked to genetic information and variation. This is a typical OCR required-practical style question.
(a) [2 marks]
- Independent: the independent variable for this topic
- Dependent: the measured outcome
(b) [2 marks]
- keep all other variables constant
- so the test is fair / only one variable is changed
(c) [2 marks]
- repeat and calculate a mean / use a tighter method
24. Grace carries out collecting valid data for genetic information and variation. This is a typical OCR required-practical style question.
(a) [2 marks]
- Independent: a chosen factor
- Dependent: a quantitative measurement
(b) [2 marks]
- calibrated instrument
- so the test is fair / only one variable is changed
(c) [2 marks]
- systematic error from zero error
25. Grace carries out drawing a graph for genetic information and variation. This is a typical OCR required-practical style question.
(a) [2 marks]
- Independent: x-variable
- Dependent: y-variable
(b) [2 marks]
- same scale / same apparatus
- so the test is fair / only one variable is changed
(c) [2 marks]
- not drawing a line of best fit through the trend
26. Grace carries out evaluating a method about genetic information and variation. This is a typical OCR required-practical style question.
(a) [2 marks]
- Independent: method change
- Dependent: precision / accuracy
(b) [2 marks]
- same sample size
- so the test is fair / only one variable is changed
27. Compare the genetic code with transcription.
[4 marks]
- triplet, degenerate, non-overlapping, universal
- DNA → mRNA in the nucleus
- give one linked difference
28. Compare transcription with translation.
[4 marks]
- DNA → mRNA in the nucleus
- mRNA + tRNA + ribosome → polypeptide
- give one linked difference
29. Compare translation with a mutation.
[4 marks]
- mRNA + tRNA + ribosome → polypeptide
- change in DNA base sequence
- give one linked difference
30. Compare a mutation with meiosis.
[4 marks]
- change in DNA base sequence
- two divisions, haploid gametes, variation
- give one linked difference
31. Apply your knowledge of speciation to this situation: allopatric vs sympatric
32. Apply your knowledge of taxonomy to this situation: binomial names