1.
State what is meant by GLP. [1]
JD SCIENCE
Good scientific practice
Answer all questions. Show working. Answers are in a separate file on the Worksheets page — do not look at them until you have finished.
2.
State what is meant by GMP. [1]
3.
State what is meant by an SOP. [1]
4.
State what is meant by validation. [1]
5.
State what is meant by verification. [1]
6.
State what is meant by calibration. [1]
7.
State what is meant by a blank. [1]
8.
State what is meant by a QC sample. [1]
9.
State what is meant by aseptic technique. [1]
10.
State what is meant by reflective practice. [1]
11.
Pat is asked about GLP in a Pearson Science paper.
(a) Describe GLP. [2]
(b) Explain why GLP is important in this topic. [3]
12.
Pat is asked about GMP in a Pearson Science paper.
(a) Describe GMP. [2]
(b) Explain why GMP is important in this topic. [3]
13.
Pat is asked about an SOP in a Pearson Science paper.
(a) Describe an SOP. [2]
(b) Explain why an SOP is important in this topic. [3]
14.
Pat is asked about validation in a Pearson Science paper.
(a) Describe validation. [2]
(b) Explain why validation is important in this topic. [3]
15.
Pat is asked about verification in a Pearson Science paper.
(a) Describe verification. [2]
(b) Explain why verification is important in this topic. [3]
16.
Pat is asked about calibration in a Pearson Science paper.
(a) Describe calibration. [2]
(b) Explain why calibration is important in this topic. [3]
17.
A balance reads 0.002 g with nothing on it. What should you do first? [3]
18.
A pipette is 0.8% high on a 10.00 cm³ check. Absolute error? [3]
19.
QC mean is 5.00, result is 5.30. Percentage difference? [3]
20.
Three QC points: 4.9, 5.0, 5.1. Mean? [3]
21.
An SOP review is every 24 months. Reviews in 6 years? [3]
22.
A waterbath is 37.0 ± 0.5 °C. Is 36.4 °C in spec? [3]
23.
Pat carries out a T-Level occupational task on good scientific and clinical practice. This is a typical Pearson required-practical style question.
(a) Identify the independent variable and the dependent variable. [2]
(b) State one control variable and explain why it must be controlled. [2]
(c) Suggest one improvement or source of error and how it affects the result. [2]
24.
Pat carries out writing or following an SOP for good scientific and clinical practice. This is a typical Pearson required-practical style question.
(a) Identify the independent variable and the dependent variable. [2]
(b) State one control variable and explain why it must be controlled. [2]
(c) Suggest one improvement or source of error and how it affects the result. [2]
25.
Pat carries out a COSHH / risk-assessment review for good scientific and clinical practice. This is a typical Pearson required-practical style question.
(a) Identify the independent variable and the dependent variable. [2]
(b) State one control variable and explain why it must be controlled. [2]
(c) Suggest one improvement or source of error and how it affects the result. [2]
26.
Pat carries out data review in a LIMS or quality log for good scientific and clinical practice. This is a typical Pearson required-practical style question.
(a) Identify the independent variable and the dependent variable. [2]
(b) State one control variable and explain why it must be controlled. [2]
(c) Suggest one improvement or source of error and how it affects the result. [2]
27.
Compare GLP with validation. [4]
28.
Compare GMP with verification. [4]
29.
Compare an SOP with calibration. [4]
30.
Compare validation with a blank. [4]
31.
Apply your knowledge of a blank to this situation: detects contamination [3]
32.
Apply your knowledge of a QC sample to this situation: Westgard / acceptance rules [3]